Linear 1 3-diarylpropanoids
Medchemexpress LLC (R)-(-)-1,2-propanediol | 4254-14-2 | MFCD00066248 | 10g
(R)-(-)-1 2-Propanediol is a (R)-enantiomer of 1 2-Propanediol that produced from glucose in Escherichia coli expressing NADH-linked glycerol dehydrogenase genes[1]
Medchemexpress LLC Avobenzone | 70356-09-1 | 98.0% | 10 MM 1 ML
Avobenzone is a dibenzoylmethane compound that is widely used as a filter in sunscreens for skin photoprotection in the UVA band. It is also identified as an endocrine disruptor that directly binds to estrogen receptor β and functions as an estrogen agonist.
- Long-Wave UVA Filter.
- Significantly promotes adipogenesis in hBM-MSCs at an EC50 of 14.1 μM.
- Up-regulates mRNA levels of PPARγ during adipogenesis in hBM-MSCs at 10 μM.
- Inhibits proliferative activities of human trophoblast cells and induces apoptosis in HTR8/SVneo cells at concentrations of 1-50 μM over 48 hours.
- Exhibits weak ERα agonism and weak AR antagonism.
Medchemexpress LLC 1,3-Propanedione, 1,3-diphenyl- | 120-46-7 | 98.0% | 224.26 | 1 ML
Dibenzoylmethane is a minor ingredient in licorice that activates Nrf2, playing a role in preventing various cancers and oxidative damage. It acts as an analog of curcumin, causing dissociation from Keap1 and nuclear translocation of Nrf2. It is provided for research use only.
- Activates Nrf2 pathway
- Analog of curcumin
- Prevents cancers and oxidative damage
- Increases HO-1 and Nrf2 protein expression
- Protects against CCl4-induced liver damage in wild-type mice
Apexbio Technology LLC Avobenzone 70356-09-1 10mM (in 1mL DMSO)
Avobenzone (70356-09-1) is a small-molecule agonist targeting estrogen receptor (ER ) It is designed to bind directly to ER thereby modulating endocrine signaling pathways Avobenzone exerts its biological activity primarily through direct receptor binding and estrogenic agonist activity Based on these properties Avobenzone holds research potential in studies investigating endocrine-disrupting chemicals mechanisms of photoprotection UV-induced cellular damage and skin pathology